1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 5-bromo-3-(chloromethyl)-, 1,1-dimethylethyl ester
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate
CAS: 1234616-42-2
Molecular Formula: C13H14BrClN2O2
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 5-bromo-3-(chloromethyl)-, 1,1-dimethylethyl ester - Names and Identifiers
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 5-bromo-3-(chloromethyl)-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C13H14BrClN2O2 |
| Molar Mass | 345.62 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD17015935 |
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 5-bromo-3-(chloromethyl)-, 1,1-dimethylethyl ester - Introduction
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate is an organic compound with the formula C14H15BrClN2O2.
Nature:
-Appearance: Colorless to light yellow or light brown solid
-Solubility: Soluble in some organic solvents, such as ethanol, dichloromethane and dimethylformamide
-Melting point: about 80-85°C
-Boiling point: about 428°C
-Density: approx. 1.44g/cm³
Use:
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate is widely used in organic synthesis, mainly as an intermediate. It can be used in the synthesis of various organic compounds, such as drugs, pesticides and dyes.
Preparation Method:
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate has many preparation methods. One common method is to react 2-bromopyridine with tert-butyl chloroacetate to generate tert-butyl 2-(chloromethyl) pyridine-4-carboxylate, and then react with silver nitrite to obtain tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate.
Safety Information:
tert-Butyl the exact toxicity and danger of 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate has not been reported in detail, as an organic compound, the following safety measures should generally be taken:
-Avoid inhalation, contact with skin or ingestion
-Use personal protective equipment such as chemical protective gloves, goggles and face shields
-Operate in a well-ventilated area
-Store and handle in accordance with local regulations
Nature:
-Appearance: Colorless to light yellow or light brown solid
-Solubility: Soluble in some organic solvents, such as ethanol, dichloromethane and dimethylformamide
-Melting point: about 80-85°C
-Boiling point: about 428°C
-Density: approx. 1.44g/cm³
Use:
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate is widely used in organic synthesis, mainly as an intermediate. It can be used in the synthesis of various organic compounds, such as drugs, pesticides and dyes.
Preparation Method:
tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate has many preparation methods. One common method is to react 2-bromopyridine with tert-butyl chloroacetate to generate tert-butyl 2-(chloromethyl) pyridine-4-carboxylate, and then react with silver nitrite to obtain tert-Butyl 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate.
Safety Information:
tert-Butyl the exact toxicity and danger of 5-bromo-3-(chloromethyl)pyrrolo[2,3-b]pyridine-1-carboxylate has not been reported in detail, as an organic compound, the following safety measures should generally be taken:
-Avoid inhalation, contact with skin or ingestion
-Use personal protective equipment such as chemical protective gloves, goggles and face shields
-Operate in a well-ventilated area
-Store and handle in accordance with local regulations
Last Update：2024-04-09 02:00:58
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